Table 3 Age at diagnosis in relation to breast cancer-specific mortality with stratification for axillary lymph node status
From: Age at diagnosis in relation to survival following breast cancer: a cohort study
Axillary lymph node status | Age at diagnosis (years) | Subjects | Person-years | Breast cancer deaths (all deaths) | Breast cancer mortality/10,000 a | Relative risk (95% CI) | Relative risk b (95% CI) | Relative risk c (95% CI) | |
|---|---|---|---|---|---|---|---|---|---|
Negative | 5- year follow-up | <40 | 84 | 399 | 11 (12) | 276 | 2.65 (1.23-5.70) | 2.40 (1.11-5.17) | 1.91 (0.88-4.19) |
40-49 | 313 | 1,531 | 16 (23) | 105 | 1.00 | 1.00 | 1.00 | ||
50-59 | 434 | 2,052 | 32 (48) | 156 | 1.50 (0.82-2.73) | 1.68 (0.92-3.06) | 1.64 (0.90-3.02) | ||
60-69 | 579 | 2,761 | 29 (65) | 105 | 1.01 (0.55-1.86) | 0.92 (0.49-1.71) | 0.87 (0.46-1.64) | ||
70-79 | 373 | 1,661 | 29 (81) | 175 | 1.70 (0.92-3.12) | 1.50 (0.81-2.80) | 1.35 (0.71-2.58) | ||
≥80 | 123 | 488 | 10 (57) | 205 | 2.03 (0.92-4.47) | 1.69 (0.76-3.78) | 1.88 (0.82-4.30) | ||
All | 1,906 | 8,890 | 127 (286) | 143 | |||||
10-year follow-up | <40 | 84 | 741 | 15 (18) | 202 | 1.69 (0.92-3.09) | 1.53 (0.84-2.81) | 1.29 (0.70-2.38) | |
40-49 | 313 | 2,912 | 35 (47) | 120 | 1.00 | 1.00 | 1.00 | ||
50-59 | 434 | 3,881 | 58 (90) | 149 | 1.25 (0.82-1.90) | 1.38 (0.90-2.10) | 1.44 (0.94-2.20) | ||
60-69 | 579 | 5,119 | 57 (143) | 111 | 0.93 (0.61-1.41) | 0.89 (0.58-1.36) | 0.90 (0.58-1.38) | ||
70-79 | 373 | 2,860 | 60 (187) | 210 | 1.75 (1.15-2.66) | 1.55 (1.01-2.37) | 1.51 (0.97-2.35) | ||
≥80 | 123 | 714 | 13 (98) | 182 | 1.54 (0.81-2.91) | 1.25 (0.66-2.38) | 1.44 (0.74-2.78) | ||
All | 1,906 | 16,228 | 238 (583) | 147 | |||||
Positive | 5- year follow-up | <40 | 75 | 301 | 28 (32) | 930 | 1.19 (0.78-1.82) | 1.33 (0.87-2.04) | 1.07 (0.69-1.66) |
40-49 | 274 | 1,141 | 89 (95) | 780 | 1.00 | 1.00 | 1.00 | ||
50-59 | 376 | 1,498 | 130 (139) | 868 | 1.12 (0.85-1.46) | 1.23 (0.94-1.61) | 1.29 (0.98-1.70) | ||
60-69 | 383 | 1,526 | 128 (158) | 839 | 1.08 (0.82-1.41) | 1.20 (0.92-1.58) | 1.30 (0.98-1.72) | ||
70-79 | 283 | 1,059 | 86 (134) | 812 | 1.05 (0.78-1.41) | 1.11 (0.82-1.50) | 1.21 (0.88-1.66) | ||
≥80 | 124 | 383 | 47 (81) | 1,227 | 1.60 (1.13-2.29) | 1.38 (0.96-1.98) | 1.68 (1.14-2.25) | ||
All | 1,515 | 5,908 | 508 (639) | 860 | |||||
10-year follow-up | <40 | 75 | 472 | 42 (46) | 890 | 1.39 (0.98-2.00) | 1.55 (1.09-2.21) | 1.34 (0.94-1.93) | |
40-49 | 274 | 1,954 | 121 (128) | 619 | 1.00 | 1.00 | 1.00 | ||
50-59 | 376 | 2,530 | 177 (198) | 700 | 1.13 (0.90-1.42) | 1.25 (0.99-1.57) | 1.26 (1.00-1.60) | ||
60-69 | 383 | 2,461 | 174 (228) | 707 | 1.12 (0.89-1.42) | 1.25 (0.99-1.58) | 1.27 (1.00-1.63) | ||
70-79 | 283 | 1,580 | 112 (217) | 709 | 1.10 (0.85-1.42) | 1.14 (0.88-1.48) | 1.22 (0.93-1.60) | ||
≥80 | 124 | 523 | 53 (106) | 1,013 | 1.54 (1.11-2.13) | 1.30 (0.93-1.81) | 1.61 (1.13-2.28) | ||
All | 1,515 | 9,520 | 679 (923) | 713 | |||||