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Table 5 Chemotherapy response rate according to the alteration in NLR and PLR before the second cycle of treatment

From: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict chemotherapy outcomes and prognosis in patients with colorectal cancer and synchronous liver metastasis

Response

NLR

PLR

Group 1 (N = 41)

Group 2 (N = 8)

Group 3 (N = 6)

p value

Group 1 (N = 31)

Group 2 (N = 11)

Group 3 (N = 13)

p value

Objective response rate (CR + PR), % (cases)

20% (8)

25% (2)

0 (0)

0.070

19% (6)

18% (2)

0 (0)

0.126

Disease control rate (CR + PR + SD), % (cases)

56% (23)

38% (3)

0 (0)

0.038*

61% (19)

45% (5)

15% (2)

0.025*

  1. NLR: group 1, <4; group 2, ≥4 → <4; group 3, ≥4 → ≥4. PLR: group 1, <150; group 2, ≥150 → <150; group 3, ≥150 → ≥150
  2. *A p value ≤0.05 was considered statistically significant. (group 2 compared with group 3)