Table 1 Cohort characteristics between neoadjuvant chemotherapy (NAC) and non-neoadjuvant chemotherapy (non-NAC) groups
| Â | NAC | Non-NAC | p-value |
|---|---|---|---|
Number [%] | 111 [34] | 215 [66] | Â |
Age (mean years [SD]) | 54.5 [13.9] | 56.7 [14.2] | 0.23 |
Male (%) | 42 | 40 | 0.49 |
ASA (median [range]) | 3 [0–4] | 3 [0–4] | 0.10 |
ECOG (median [range]) | 1 [0–2] | 1 [0–3] | 0.06 |
Primary tumour location | Â | Â | 0.29 |
Right colon (n [%]) | 48 [46.2] | 91 [48.7] | Â |
Left colon (n [%]) | 41 [39.4] | 62 [33.2] | Â |
Rectum (n [%]) | 15 [14.4] | 34 [18.2] | Â |
Tumour markers | Â | Â | Â |
CEA (mean [SD]) | 45 [248] | 29 [167] | 0.10 |
CA 19.9 (mean [SD]) | 45 [91] | 60 [272] | 0.69 |
CA 125 (mean [SD]) | 22 [39] | 38 [108] | 0.16 |
Operative outcome | Â | Â | Â |
PCI (median [range]) | 9 [1–39] | 8 [1–35] | 0.15 |
CC-0 score (n [%]) | 104 [93.7] | 206 [95.8] | 0.14 |
HIPEC (n [%]) | 98 [88.3] | 197 [91.6] | 0.38 |
Morbidity~ (n[%]) | 33 [29.7] | 68 [31.6] | 0.82 |
Perioperative mortality (n [%]) | 1 [0.9] | 2 [0.93] | 0.97 |